Denaturing HPLC-Based Approach for Detecting RYR2 Mutations Involved in Malignant Arrhythmias
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چکیده
منابع مشابه
Denaturing HPLC-based approach for detecting RYR2 mutations involved in malignant arrhythmias.
BACKGROUND Mutations in the RYR2 gene, which encodes the cardiac ryanodine receptor, have been reported in patients showing either arrhythmogenic right ventricular cardiomyopathy, type 2, or stress-induced polymorphic ventricular tachycardia. Both clinical phenotypes are characterized by a high risk of sudden death. Detection of RYR2 mutations is particularly important because beta-blocker trea...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2004
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2003.030734